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lakshmi
India-Tamilnadu-Madurai
PRE CLINICAL RESEARCH
To pursue a challenging career by joining in your organization, which provides me an environment that is professionally challenging and personally rewarding in which I can apply my skills, acquire new knowledge and contribute constructively
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RESEARCH EXPERIENCE
working as a Junior Research Fellow in Department of Biochemistry, Sri Ramachandra University,Chennai-116,working pre clinical research in DST project from jun 2006 till date
TECHNIQUES KNOWN
Biochemical techniques
o Analysis of tissue or plasma anti-oxidant profile (SOD, CAT, GPX,GSH, lipid peroxidation, NO etc.,)
o Plasma/serum metabolites
Preclinical Pharmacological screening techniques
o Anti-inflammatory and Analgesics
o Anti-diabetics
o Anti-hyperlipidemics (acute and high fat diet models)
o Anti-hypertensive
o Anti-arthritics
o Anti-ulcer
o Toxicity studies (Acute, sub-acute and chronic models)
Rodent surgical techniques
o Pylorus legation
o Renal legation
o Rodent survival surgery technique
Phytochemistry
o Identification and Isolation of active principles/ constituents in herbal extracts
o Herbs secondary metabolites qualitative and quantitative analysis
o Chromatographical standardization of herbs/herbal products
INSTRUMENTS HANDLED
Chromatographic
o HPLC-UV detector-Perkin Elmer series 200 (Total Chrom Workstation 6.3)
o Agilent 1100 series-chemstation software, shimadzu -Echrome software
º Gas Chromatograph: ( Agilent –6890-chemstation software)
o HPTLC – CAMAG 4. (Wincats 1.3.4)
Spectral
o Ultra violet and visible spectrophotometer - Perkin Elmer Lambda 25 (Winlab 2.85.04)( chemito 2100 series-class software, shimadzdu-uv probe softer
o Atomic Absorption spectrophotometer - Perkin Elmer series 400 (Winlab 32)
o Spectrofluorimeter - Perkin Elmer LS 45
o ELISA – BioRad (Model 680)
Rodent Physiological data acquisition system for invasive blood pressure, body temperature and, ECG. (ISO SYS)
Semi-automatic biochemical analyser (Rapid star 21plus)
Hematocytometer – blood cell analyser (BC 2080)
Seeking assignments in Quality control operations in a frontline organization.
Summary of Skills and Experience
A qualified bio-chemist with over 2 years (from may-2004-2006) of experience in quality control & product testing in drug manufacturing pharmaceutical industry. A keen planner, strategist & implementer with experience in planning/monitoring quality control operations for Anti diabetic and anti inflammatory synthetic Active Pharmaceutical ingredients (API) &Trial batch operations. Monitoring adherence to quality systems & managing the quality auditing procedures from. KUMAR ORGANIC PRODUCTS LIMITED (An ISO 9001 & 14001 and WHO GMP certified company & Fine chemicals manufacturing company) at Bangalore
Areas of Expertise and Exposure:
Quality Control Executive:
О Maintaining Sops, manuals & work instructions for quality control operations
О Monitoring stability studies....
О Sampling and testing of raw materials, intermediates and final products.
О Preparation and maintenance of working standards, Calibration of instruments.
О Handled Antidiabetic, antibacterial antifungus, anitiarthritis Active
Pharmaceutical Ingredients. As per ICHQ-7A Guidelines
О Handling calibration of the Instruments like HPLC,GC,UV-VIS Spectrophotometer, HPTLC
And Polari meter, Karl fisher Apparatus, melting point apparatus
О Experience in doing wet analysis, as per IP BP USP Basis analysis..
PAPER PRESANTATION/ CONFERENCES ATTENDED
Presented a poster titled “Failure of Nimodipine to prevent Ischemic neuronal damage in middle cerebral artery occluded Sprague dawely rats”Saravana Babu C,Lakshmi Sundaram R, Gayathri V, Sunil AG, Hannah R. Vasanthi and Ramanathan MT in the Symposium on “Bioresources in the Development of Medicine” & 28th Annual Conference of Indian Association of Biomedical Scientists, September 2007.
2. Presented paper titled “Protective Role of a Polyherbal Formulation (R05) on Oxidative Stress in Streptozotocin Induced Diabetic Rats, Hannah R Vasanthi, Saravana Babu C, Lakshmi sundaram R, Sangeetha M.K. in the International Conference on Free Radicals and Natural Products in Health (FRNPH-2008) and 7th Annual Meeting of Society of Free Radical Research, India at University of Rajasthan, Jaipur, February 14-16th 2008.
3 .Saravana Babu, Laksmi Sundaram.R, A.G Sunil, Hannah R Vasanthi. “The Glucose Paradox of Cerebral Stroke: Nimodipine can be Neuroprotective?” in the Annual conference of the Indian Society of Atherosclerosis Research-“Recent Approaches in Atherosclerosis Research”, 16th and 17th December 2006 at Madras University, Chennai. BEST PAPER AWARD.
4. Attended the workshop and lecture session in The First Indian congress on alternatives to the use of animals in research, testing and education at Sri Ramachandra University, Chennai, India on 29th and 31st January 2007.
PERSONAL PROFILE
Address : Athanoor ,Alanganallur (via),Madurai-625503
Date of Birth/ Sex : 02.05.1979/ male
Marital Status : Unmarried.
Nationality : Indian
REFERENCES
1) R. paramasivan,
Assistant director (department of molecular biology)
Center for Research medical Entomology
No 4, sarojini street,
Chinnachokkikulam,
Madurai
NO: 09442026705 2) C. saravanababu PhD
Senior Research fellow
Sre Ramachandra university
Porur, chennai
NO:09884500081
DECLARATION
I hereby declare that the information furnished above is true and I will contribute my best of my knowledge.
Place: Chennai sincerely
Date: 20:06:2008 R. LAKSHMISUNDARAM
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