Junior Research Fellow Resumes in India-Karnataka-Bangalore: Malini

Junior Research Fellow Resume

Contact Candidate

Name:

Malini

Location:

India-Karnataka-Bangalore

Experience:

1-3 yrs

Willing to Relocate:

Willing to Travel:

Yes

Most Recent Job Title:

Junior Research Fellow

Personal Website:

Objective:

Seeking a position to utilise my skills and abilities in the lifescience industry that offers security and professional growth while being resourceful, innovative and flexible.

Resume Text:

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Laser Raman spectra of statistically significant number of malignant and normal oral tissue samples. To develop and establish an objective statistical evaluation method for discrimination between malignant and normal oral tissues and evaluate the suitability of the model by testing sufficient number of blind runs for comparison with pathological results from same samples for routine use in diagnosis and screening in oral malignancy.
Responsibilities: I have recorded Raman spectra of normal, gingival (inflammatory), premalignant and malignant oral tissue samples and analysed the data by Principal Component Analysis (PCA) using GRAMS 32 software. I have developed standard calibration models for each class of samples and evaluated the methodology for discriminating normal from gingival, premalignant and malignant oral tissues. To evaluate the efficacy of the model, I have also carried out "blind studies", where the nature of the sample is not known to the spectroscopist.

 February 2003- August 2003.
Worked as an Assistant facilitator at Amdon BioVigyan Pvt. Ltd, Delhi.
I have taken an active part in developing and implementing a comprehensive in-house training program. I have assisted in course development and classroom instruction.

 Oct 2001- February 2002.
Worked as a Bioinformatics trainee at M/S. Manvish Infotech Ltd, Bangalore.

PUBLICATIONS
• Malini R, Venkata Krishna K., Kurien J, Keerthilatha M. Pai, Lakshmi Rao, Kartha VB and Murali Krishna C. “Discrimination of normal, inflammatory, pre-malignant and malignant oral tissue: A Raman Spectroscopy Study, Biopolymers, 81, 179-193, 2006.
• Malini.R, Kurien J, Keerthilatha M. Pai, Lakshmi Rao, Kartha VB and Murali Krishna C, Raman Spectroscopy study of normal, inflammatory, pre-malignant and malignant oral tissue: A preclinical study, Dent Update, Under Preparation.
• C. Murali Krishna, N.B. Prathima, B.M. Vadhiraja, R.Malini, Donald Fernandes, M.S. Vidyasagar and V.B. Kartha, Raman spectroscopy studies for diagnosis of cancer in human uterine cervix, Vibrational Spectroscopy, In Press 2006.
• K.Maheedhar, Rani A. Bhat, Malini R., Prathima N.B, Keerthi, Prahlad Kushtagi and C.Murali Krishna, “Diagnosis of Ovarian Cancer by Raman Spectroscopy: A Pilot Study, Current Science, Communicated.

Refereed Communications:
Proceedings:
Conferences: International

• M.S. Vidyasagar, N.B. Prathima, R.Malini, B.M. Vadhiraja, V.B. Kartha, C. Murali Krishna, HPLC-LIF for diagnosis of cervical cancers, Manipal Oncology Society, Kaulalampur, Malaysia 2004.

• B.M.Vadhiraja, R.Malini, Donald J. Fernandes, V.B.Karhta, M.S.Vidyasagar and C.Murali Krishna, Raman Spectroscopy Studies for Prediction of Radiation Response of Cervical Cancers, 1st Meeting of Young Radiation Scientists in Asia, Hiroshima, Japan 2005.

National:

• Malini R, Prathima.N.B, Keerthilatha M.Pai, V.B. Kartha and C. Murali Krishna, ‘Raman spectroscopy Studies of Oral Cancer’, NLS05, BARC, 2005.
• Malini R, Aparna Aggarwal, Prathima N.B., Keerthilatha M. Pai, V. B. Kartha and C. Murali Krishna, “Evaluation of Raman Spectroscopic Diagnostic Methods for oral Cancer”. Discussion Meeting on Advances in Spectroscopy (DMAS-2005) at I.I.Sc. Bangalore, India. February - 21-24, 2005.
• Malini R, Jacob Kurien, Stanely Mathew, N.B.Prathima, V.B.Kartha and C.Murali Krishna, 'Raman Spectroscopy in Tissue Typing in Breast Cnacers', AROICON 2004, Ludhiana.
• C.Murali Krishna, Rani A. Bhat, Prathima N.B, Malini R, Keerthi, Prahlad Kusthagi and V.B. Kartha,' A Raman Spectroscopy Study of Ovarain Tumors' NLS05, BARC, 2005.
• Prathima N.B, B.M. Vadhiraja, Rani A. Bhat, Keerthi, Malini R, Donald Fernandes,, Prahlad Kushtagi, M.S. Vidyasagar, V.B. Kartha and C. Murali Krishna,'Raman Spectroscopic Monitoring of Radiation therapy in Cancer of Cervix', NLS05, BARC, 2005.

ACADEMIC PROJECT
“Protein modeling of rpb11 and dbp8 from Saccharomyces ceveresiae”.
The objective was to model a protein (dbp8) in yeast using MODELLAR software and verify its accuracy, thereby reducing the time taken by experimental biologist to predict the structure by wet lab experiments. Another protein rpb11 was modeled using an online tool Swiss Model.

Place: Manvish Infotech Ltd.
Duration: 6 weeks.

TRAINING
An advanced diploma course in Bioinformatics (2001).

Place: Manvish Infotech Ltd, Bangalore
Duration: 3 months.

Computer Skills: Operating Systems DOS, Windows, Unix
Languages C, HTML, Perl
MS-Office, Internet.

Bioinformatics Knowledge:

Sequence searching and Alignment tools like BLAST, FASTA, and CLUSTAL W
Sequence analysis using EMBOSS.
Prediction of secondary structure of proteins using JPRED and Chow-Fasman method, Protein folding and Drug Discovery.
Homology based protein modeling using MODELLER, SWISS MODEL, RASMOL, CLUSTAL X, PDB-BLAST, VERIFY 3D, PROCHECK.
Microarray Technology.
Basic manipulations with DNA sequences, Molecule design, molecule editing, Gel lsctrophoresis, PCR analysis and Primer design using Vector NTI, editing chromatograms.

ACADEMIC PROFILE
2000 M.Sc. Microbiology(63.1%) Maharani’s Science College, Bangalore

1998 B.Sc (CBM) (Microbiology 62%) S.J.R College for Women, Bangalore.

PERSONAL DETAILS
Date of Birth: 28th April 1977
Marital status: Married
Husband’s Name: M.G.Gopinath
Sex: Female
Languages known: English, Hindi, Kannada, Telugu.

Highly inquisitive, creative and resourceful.
Excellent skills in communication and collaboration.
Exicted by the challenge of research and experimentation.

REFERENCES
1. Dr. Murali Krishna CHILKAPATI
Scientific Officer 'E' and Principal Investigator
Chilakapati Laboratory
Advanced Center for Training, Research and Education in Cancer (ACTREC),
Tata Memorial Center (TMC)
Kharghar, Sector '22'
Navi Mumbai - 410208
INDIA
mchilakapati@actrec.gov.in, krishna.murali@univ-reims.fr
Telephone: +91-22-2740 5039

2. Dr.V.B.Kartha Ph.D; FNA, FASc
21 Udaygiri Hsg Socy,
Opp. Telecom Factory,
Sion-Trombay Road,
Deonar, Mumbai-400088
Tel- 022-25564908
e-mail:bhasikartha@gmail.com
sbkartha@hotmail.com

DECLARATION
I hereby declare that the information furnished above is true to the best of my knowledge and confident of my ability to work in a team.

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